Basic characteristic and life style for clinical outcome of CAD patients in Taiwan

Hsin-Bang Leu
Taipei Veterans General Hospital Healthcare and Services Center
Cardiovascular Research Center, National Yang-Ming University, Taipei, Taiwan

 Cardiovascular (CV) disease is associated with increased risk of mortality and morbidity,
 and is the leading cause of death worldwide. Atherosclerosis, a chronic inflammatory process in the vessels leads to vascular damage, atheroma formation, vessel occlusion and
 even plaque rupture is believed to play a central role in CV disease. However, despite great efforts including the improvement of new drug and intervention treatment, the occurrence of adverse events including acute coronary syndrome (ACS), stroke, cardiac death, and revascularization persists still can not
 be completely avoided, especially in high-risk CAD patients after coronary intervention. Therefore looking for good
 indicator in addition to current prognostic indication may provide additional predictive values. Our current work would like to conduct a cohort to monitor the outcomes prospectively in CAD patients after coronary intervention and looking for new biosignatures including any signatures from images, biochemical or clinical profiles to early identify patients at risk.
  Finally, given the potential difference in diet, culture, and physical background between Western and Asian people, the dietary habit, personality trait as well as lifestyle factors will be incorporated together to investigate the role of dietary, personality as well as lifestyle modification for long-term outcome in CAD cohort.

Reference
1: Leu HB, Yin WH, Tseng WK, Wu YW, Lin TH, Yeh HI, Cheng Chang K, Wang JH, WuCC, Chen JW. Impact of type D personality on clinical outcomes in Asian patients with stable coronary artery disease. J Formos Med Assoc. 2018 Sep 19. pii:S0929-6646(16)30469-7. doi: 10.1016/j.jfma.2018.08.021. [Epub ahead of print] PubMed PMID: 30243505.
2: Leu HB, Yin WH, Tseng WK, Wu YW, Lin TH, Yeh HI, Chang KC, Wang JH, Wu CC, Chen JW. Identification of new biosignatures for clinical outcomes in stable coronary artery disease – The study protocol and initial observations of a prospective follow-up study in Taiwan. BMC Cardiovasc Disord. 2017 Jan 28;17(1):42. doi: 10.1186/s12872-017-0471-z. PubMed PMID: 28129736; PubMed Central PMCID: PMC5273790.